Table 2.

randomized, double blinded, controlled clinical trials for stem cell mobilisation

Trial	No. of patients	Treatment	Follow up (months)	Follow up (method)	Change in LVEF (%) (Treatment vs. control)	p-value
REVIVAL-2 [62]	114	G-CSF	6	MRI	0.5±3.8 vs. 2.0±4.9	NS
STEMMI [63]	78	G-CSF	6	MRI	8.5 vs. 8	NS
G-CSF-STEMI [64]	44	G-CSF	3	MRI	6.2±9.0 vs. 5.3±9.8	NS
Ellis [65]	18	G-CSF	1	ECHO	4.5±11.3/5.2±6.7 vs. 8.0±9.9	NS
HEBE III*[66]		EPO	1,5	PVR	ongoing	--

^*not double blinded;

LVEF = left ventricular ejection fraction;

G-CSF = granulocyte colonie stimulating factor;

EPO = Erythropoietin;

MRI = magnetic resonance imaging;

ECHO = echocardiography;

PVR = planar radionuclide ventriculography

NS = not significant