Table 7.
Comparison of characteristics between HIV-TB patients without and with TB-IRIS and HIV patients with ART associated TB.
| No TB-IRIS | TB-IRIS | ART-associated TB | |
|---|---|---|---|
| (n = 118) | (n = 5) | (n = 6) | |
| Age (yrs) | 37 ± 10 | 31 ± 7 | 35 ± 15 |
| Sex (% male) | 80 | 80 | 50 |
| BMI (kg/m2) | 19 ± 5 | 18 ± 3 | 19.4 ± 4 |
| ATT-ART (days) | 32 (21–70) | 20 (18–27) | — |
| ART-IRIS (days) | — | 73 (6–84) | 37 (7–88) |
| CD4 (cells/μl) | 136 (70–225.75) | 167 (118–193) | 132 (57.25–182.75) |
| Increase in CD4 (cells/μl) | 89 (32.25–144.75) | 229 (61–283) | 161 (129–316) |
| Increase in CD4 (%) | 57.6 (24–181) | 119 (63.5–207) | 160 (72–369) |
| VL (log10 copies/ml) | 5.21 (4.76–5.65) | 5.49 (5.18–5.63) | 5.28 (4.95–5.51) |
| Decrease in VL (log10 copies/ml) | 5.19 (4.76–5.63) | 5.49 (5.18–5.63) | 5.13 (4.87–5.39) |
| Decrease in VL (%) | 99.58 (98.85–99.9) | 99.93 (99.91–99.97) | 99.91 (99.84–99.93) |
BMI: body mass index; ATT: antituberculosis treatment; ART: antiretroviral treatment; VL: viral load
Age and BMI are presented as mean ± SD; gender as % of male and ATT-ART gap, ART-IRIS gap, CD4 cell counts and viral load as median and IQR.