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. 2010 Sep 20;2010:601098. doi: 10.4061/2010/601098

Figure 3.

Figure 3

Effect of SR140333 administration, either 30 minutes before or 1 hour after CLP, on lung (a) Phospho ERK1/2 and (b) Phospho-PKCα. Results shown are the mean ±S.E.M (n = 6 in each group). “Vehicle + CLP” and “SR140333 + CLP” represent the groups that received vehicle and SR140333 treatment, respectively, commencing 30 minutes prior to CLP. “CLP + vehicle” and “CLP + SR140333” represent the groups that received vehicle and SR140333 treatment, respectively, 1 hour after CLP. Upper panels show representative western blot gel pictures of phosphorylated and total ERK1/2 and PKCα for each of the groups. *P < .05 when vehicle-treated CLP animals were compared with sham group animals; **P < .05 when SR140333-treated CLP animals were compared with vehicle-treated CLP animals. CLP: cecal ligation and puncture; ERK: extracellular signal regulated kinase; IOD: integrated optical density; PKC: protein kinase C.