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. 2010 Sep 20;2010:601098. doi: 10.4061/2010/601098

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Copyright © 2010 Akhil Hegde et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of GR159897 administration 1 hour after CLP on lung (a) neutrophil infiltration (MPO), (b) CXCL-2, (c) CCL-2, (d) IL-1β and (e) IL-6 levels. Results shown are the mean ± S.E.M (n = 6–9 in each group). “CLP + vehicle” and “CLP + SR140333” represent the groups that received vehicle and SR140333 treatment, respectively, 1 hour after CLP. *P < .001 when vehicle-treated CLP animals were compared with sham group animals. CLP: cecal ligation and puncture; IL: interleukin; MPO: myeloperoxidase.