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. 2011 Jan;17(1):54–63. doi: 10.1261/rna.2498411

FIGURE 5.

FIGURE 5.

Ago1- but not Ago2-bound hp-esiRNAs are destabilized by highly complementary target RNAs. (A) Size distribution of genome-matching (top) and prefix-matching (bottom) esi-2.1 sequences associated with Ago1 (left) or Ago2 (right) in S2 cell extracts. The most abundant 3′ nontemplated, added nucleotides are noted. (B) The abundance of esi-2.1 (top) or all other small RNAs from the esi-2 locus (bottom) associated with Ago1 (red) or Ago2 (blue) in S2 cell extracts. (C) Size distribution of small RNAs, other than esi-2.1, derived from the esi-2 locus and associated with Ago1 (top) or Ago2 (bottom) in S2 cell extracts. (D) Size distribution of genome-matching (top) and prefix-matching (bottom) small RNAs from the esi-1 locus associated with Ago1 (left) or Ago2 (right) in S2 cell extracts. The most abundant 3′ nontemplated, added nucleotides are noted.