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AZD6244 activity against individual solid tumor xenografts, Kaplan-Meier curves for EFS, median relative tumor volume graphs, and individual tumor volume graphs are shown for selected lines: (A) OS-1 (B) OS-33, and (C) BT-39. Mice received AZD6244 (100 mg/kg BID x 5 (Monday-Friday) and once daily (SID) (Saturday-Sunday) [abbreviated BID × 5/SID × 2] for six consecutive weeks
