Table 1.

Fournier's gangrene or genital infection associated with hematologic malignancies: a summary of the reported cases

Case	Age/sex	Onset of Fournier's gangrenea	Hematologic malignancy	Clinical feature of the onset	Clinical feature of the severest situation	Phlogogenous bacteria
Naithani et al., 2008 [6]	17/M	after diagnosis	acute promyelocytic leukemia	painful vesicular lesions in scrotum	ulcers	Staphylococcus aureus, Escherichia coli
Mantadakis et al., 2007 [7]	21/M	after diagnosis	acute lymphoblastic leukemia	scrotal edema	a small necrotic scrotal eschar	Pseudomonas aeruginosa, Staphylococcus epidermidis
Fukuno et al., 2003 [8]	43/M	after diagnosis	acute promyelocytic leukemia	an ulcer of 0.5 cm in diameter on the left side of the scrotum	swelling that was improved by a surgical incision	no description
Bakshi et al., 2003 [9] 1st case	6/M	after diagnosis	acute myeloid leukemia	edema over the prepuce	a necrotic ulcer	Pseudomonas aeruginosa
Bakshi et al., 2003 [9] 2nd case	10/M	after diagnosis	acute lymphoblastic leukemia	pain and swelling in the prepuce	abscess	Pseudomonas aeruginosa
Bakshi et al., 2003 [9] 3rd case	9/M	after diagnosis	non-Hodgkin lymphoma	severe pain during micturition, erythema, and tenderness in the penile region	gangrenous changes on the prepuce and glans	no description
Yoshda et al., 2002 [10]	16/M	after diagnosis	acute myelogenous leukemia	penile swelling with miction pain	gangrene in the regions of the scrotum, penis, thighs, and lower abdomen	Pseudomonas aeruginosa
Islamoglu et al., 2001 [5]	33/M	before diagnosis	acute myelomonocytic leukemia	scrotum edema	complete scrotal necrosis, complete penile shaft necrosis, and a left anal ulcer that extended to the left gluteal area	Bacteroides fragilis
Martinelli et al., 1998 [2] 1st case	41/M	after diagnosis	acute non-lymphocytic leukemia	genital erythema, pain, swelling and crepitation	blistering and ulceration	Pseudomonas aeruginosa
Martinelli et al., 1998 [2] 2nd case	26/F	after diagnosis	acute non-lymphocytic leukemia	redness and swelling of the right labium majorum	ulceration	Pseudomonas aeruginosa
Martinelli et al., 1998 [2] 3rd case	26/F	after diagnosis	acute non-lymphocytic leukemia	pain, edema, erythema and swelling of the perineal area	a necrotic ulcer	Pseudomonas aeruginosa
Faber et al., 1998 [4]	50/M	before diagnosis	acute myelogenous leukemia	progressive perianal pain	a diffusely infiltrated anal region and bluish scrotum	Escherichia coli
Levy et al., 1998 [11]	44/M	after diagnosis	acute promyelocytic leukemia	small indurated lesion of the right scrotum	a painful necrotic area 4×5 cm	Streptococcus faecalis, Staphylococcus coagulase negative

^aThe onset of Fournier's gangrene or genital infection before or after the diagnosis of a hematologic malignancy.