Table 1.
Viard 1998 [2] | Trent 2003 [9] | Prins 2003 [3] | Campione 2003 [10] | Al-Mutairi 2004 [11] | Shortt 2004 [12] | Tan 2005 [13] | Stella 2007 [14] | Bachot 2003 [15] | Brown 2004 [16] | Schneck 2008 [17] | |
---|---|---|---|---|---|---|---|---|---|---|---|
Study | PNC | RNC | RNC | PNC | PNC | RNC | RNC | RC | PNC | RNC | RC |
Patients | 10 | 24 | 48 | 10 | 12 | 16 | 12 | 23 | 34 | 24 | 75 |
Detach, % | 39 | 44 | 45 | 49 | 58 | 65× | × | × | 19 | 49 | × |
Dose IVIG, g/kg | 3 | 4 | 3 | 2 | 2×5 | 2.8 | 2 | × | 2 | 1.6 | 1.9 (0.7×2.3) |
Predicted mortality, % | × | 33 (S) | × | 35 (S) | × | 38 (A) | × | 35.8 (S) | 24 (S) | 28.6 (S) | 25 (S) |
Actual mortality, % | 0 | 4 | 12 | 10 | 0 | 25 | 8 | 26 | 32 | 41.7 | 34 |
PNC = Prospective, noncontrolled; RNC = retrospective, noncontrolled; RC = retrospective, controlled; S = SCORTEN; A = APACHE.
Initial rash involving 65 ± 29% TBSA.