Table 3.

Comparisons using the fixed cut off approach Analysis of the three cohorts using the fixed cutoff approach and comparison to the continuous approach. A: Differences between the informative genes; no value means that the gene was not selected as informative. (*) denotes genes identified previously by the same method [16]. B, C and D show 2×2 contingency tables with sensitivity (Bold upper left) and specificity (Bold lower right) indicated for each comparison. E: Sensitivity and specificity using the continuous and fixed cutoff data analysis with confidence interval in parenthesis. Note that the continuous analysis produces nearly the same or greater specificities and sensitivities, while picking fewer genes for each composite. F: Positive predictive value (PPV) and negative predictive value (NPV) for each comparison.