TABLE 2.

Identification of the protein partners of IMP-2 that change cell motility and levels of Glu-tubulin in RD and C2C12 cells and specifically impact the levels of PINCH-2 and/or MURF-3 in these cells^a

^aRNAi loss-of-function assays identify the protein partners of IMP-2 that change cell motility and levels of Glu-tubulin in RD and C2C12 cells (highlighted in gray) and specifically indicate the IMP-2 partners that impact the levels of PINCH-2 and/or MURF-3 in these cells (in boldface). Changes in cell motility were analyzed when the wound in the control cell monolayer (transfected with scrambled siRNA) was fully closed (24 h for C2C12 and 20 h for RD). Decreased motility of cells transfected with siRNAs against IMP-2 partners was considered significant if at the indicated times at least 50% of the original wound was clearly visible. Glu-tubulin levels were evaluated by Western blotting (see Fig. S5 in the supplemental material).