Table 4.
Analysis of variance for the ranked SNP Bayes factors contrasting the prior hyperparameters (default a = 1 versus a = 1/8) and method of imputation (full imputation with 100 data sets versus a modal estimate of the missing genotypes) for the 70 SNPs in the NCOCS pathway that passed the marginal screen
d.f. | Sum Sq. | Mean Sq. | F-value | Pr(> F) | |
---|---|---|---|---|---|
SNP | 69 | 1635891.00 | 23708.57 | 208.04 | <2 × 10−16 |
Prior | 1 | 169641.66 | 169641.66 | 1488.60 | 0.0000 |
Impute | 1 | 134.41 | 134.41 | 1.18 | 0.28 |
Prior:impute | 1 | 53.16 | 53.16 | 0.47 | 0.50 |
Residuals | 207 | 23589.77 | 113.96 |