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Altered multiplication kinetics of recombinant viruses. Vero cells (upper panel) or MDBK cells (lower panel) were infected with recombinant viruses at an MOI of 0.01 PFU/cell. Culture medium was harvested at the indicated times, and virus titers were measured by plaque assay on BHK-21F cells. Values represent averages from three independent experiments, with error bars indicating standard deviations.
