Skip to main content
. 2010 Dec 8;2011:758350. doi: 10.1155/2011/758350

Table 4.

Characteristics of patients with ART-associated TB.

Patient Age (years) Sex CD4 counts Baseline clinical symptoms* Baseline CXR findings Time to TB (days) TB category Basis of TB diagnosis Basis of TB- IRIS diagnosis Outcomes
Baseline (cell/μL) TB (cell/μL)
Patient 1 53 F 156 148 weight loss Possible TB 345 TB pleura cytology NA Improved
Patient 2 27 F 15 5 weight loss, anorexia Normal 79 Disseminated TB abnormal CXR culture +ve 2,4,5,6 Improved
Patient 3 31 F 90 68 cough, fever, weight loss, anorexia Normal 14 PTB culture +ve NA Improved
Patient 4 37 M 123 no symptoms Normal 24 PTB culture +ve NA Lost contact
Patient 5 42 M 116 95 cough, weight loss, anorexia Possible TB 54 PTB culture +ve NA Died
Patient 6 45 F 21 28 weight loss Normal 17 PTB AFB+ 2,5,6,7 Improved
Patient 7 28 F 24 18 no symptoms Normal 20 TB adenitis FNA AFB+ 1,5,6 Lost contact
Patient 8 43 F 206 313 no symptoms Normal 100 PTB abnormal CXR NA Improved

Abbreviations: M: Male; F: Female; TB: tuberculosis; CXR: chest X-ray; PTB: pulmonary tuberculosis; AFB+: acid fast bacilli positive; AFB−: acid fast bacilli negative; IRIS: immune reconstitution inflammatory syndrome.

*included clinical symptoms of greater than two weeks.

criteria for TB-IRIS (new or worsening): 1: adenopathy; 2: CXR abnormalities; 3: central nervous system features of TB; 4: serositis; 5: constitutional symptoms (fever, night sweats, weight loss); 6: respiratory symptoms (cough, dyspnea, stridor); 7: abdominal pain with peritonitis, hepatomegaly, splenomegaly, or adenopathy; NA: not applicable.