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. Author manuscript; available in PMC: 2010 Dec 20.
Published in final edited form as: Open Pain J. 2009 Jan 1;2:7–31. doi: 10.2174/1876386301003010001

Fig. 1.

Fig. 1

Schematic diagram illustrating interactions between neuron, microglia and astrocytes. Arrows indicate action of one cell type on other through release of chemical mediators and their binding with respective receptors. Dashed arrows show pathways to be substantiated. Note large block arrow on right illustrating increased pain as a result of neuron-glial interactions within pain processing circuitry.