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Relative 5-HT:NE in-vitro reuptake inhibition of SNRI-active drugs
| Drug name | 5-HT:NE reuptake inhibition ratio |
|---|---|
| Venlafaxine | 30:118 |
| Duloxetine | 10:118 |
| Desvenlafaxine | 10:119 |
| Amitriptyline | 8:158 |
| Milnacipran | 1:118 |
Abbreviations: 5-HT, serotonin; NE, norepinephrine; SNRI, serotonin and norepinephrine reuptake inhibitor.
