. 2009 Apr 30;1:39–48. doi: 10.2147/cmar.s4548

Table 5.

Cell cycle distribution and mitotic delay in breast cancer cell lines

Cell line	Without IR Treatment			With IR treatment			G₂delay index^a	%G₂–M^a	G₂/G₀–G₁^a	(G₂/G₀–G₁)/S^a
Cell line	%G₀–G₁^a	% S^a	%G₂–M^a	%G₀–G₁^a	% S^a	%G₂–M^a	G₂delay index^a	%G₂–M^a	G₂/G₀–G₁^a	(G₂/G₀–G₁)/S^a
MCF7^b	63.4 ± 5.6^f	18.8 ± 2.7^e	16.6 ± 2.1^e,^f	68.2 ± 3.2^e,^f	11.2 ± 1.1^f	17.5 ± 1.4^e,^f	5.6 ± 10.8^e,^f	17.5 ± 1.4^e,^f	25.8 ± 2.7^e,^f	1.4 ± 0.1^e,^f
BT-20^c	52.2 ± 15.6	13.9 ± 1.4^g	31.9 ± 14.6	41.6 ± 15.3^g	11.8 ± 1.0^g	45.2 ± 15.6	95.6 ± 14.0^g	45.2 ± 15.6	146.7 ± 117.4^g	10.3 ± 7.8
HCC1937^d	45.4 ± 6.1	20.7 ± 1.6	32.1 ± 4.0	22.3 ± 3.2	18.6 ± 1.3	56.0 ± 1.9	116.2 ± 18.2	56.0 ± 1.9 0	257.4 ± 49.70	12.4 ± 1.9
				Fold difference			20.7	3.2	10.0	8.9

Notes:

p<0.05, ANOVA test for differences among three cell lines;

MCF7 cells with wild-type BRCA1 and wild-type p53; ³⁵,⁴³

BT-20 cells with wild-type BRCA1 and mutant p53; ³⁵,³⁶

HCC1937 cells with mutant BRCA1 and mutant p53; ⁴⁴

p < 0.05, Bonferroni post hoc pair-wise comparison, MCF7 compared to BT-20 cell line;

p < 0.05, Bonferroni post hoc pair-wise comparison, MCF7 compared to HCC1937 cell line;

p < 0.05, Bonferroni post hoc pair-wise comparison, BT20 compared to HCC1937 cell line.

Abbreviation: IR, ionizing radiation.