Table II. Univariate and multivariate regression analyses of predicting factors for long-term non-progressors (LTNPs).

	Univariate			Multivariate
Variables	OR	95%CI	P-value	OR	95%CI	P-value
Gender
Female	1			1
Male	4.6	0.9, 22.4	0.032	10.2	1.1, 96	0.021
CDC stage
N/A	1
B	1.0	0.31-3.4	0.963
Log HIV-RNA at baseline	0.4	0.1- 1.2	0.081	2.1	5.8, 472.8	0.361
Total T cells
< 1412	1			1
≥1412	37.4	8.2-170.3	<0.001	67.1	9.3,485	<0.001
Naïve helper T cells
< 128	1			1
≥128	21.6	5.4-87.0	<0.001	32.2	5.9,175.3	<0.001
Memory helper T cells
< 138	1			1
≥138	21.6	5.4-87.0	<0.001	26.5	5,139.7	<0.001
Activated helper T cells
<35.5	1			1
≥35.5	4.0	1.2-13.4	0.0219	3.6	1,12.9	0.047
Cytotoxic T cells
<954	1			1
≥954	8.8	2.5-30.7	0.0004	9.7	2.4,38.9	0.001
Naive cytotoxic T cells
<176	1			1
176-292	4.6	1.1-20.4		5.3	1.1,26.5
≥292	14.3	3.1-66.0	<0.001	16	3,84.9	0.002
Memory cytotoxic T cells
<411	1			1
≥411	5.9	1.8-19.9	0.0037	6.7	1.8,25.5	0.004
Activated cytotoxic T cells
<379	1			1	1
≥379	2.8	0.9-9.2	0.0930	2.7	0.7,9.8	0.135
B cells
<216	1			1
216-285	3.4	0.83-14.2		5.5	1.1,29
≥ 286	22.1	3.9-124.3	<0.001	30.7	4.4,214.5	<0.001
Natural killer cells
<108	1			1
≥108	1.9	(0.6-6.4)	0.2873	1.5	0.4,5.5	0.569

LTNP is defined as antiretroviral-naive, HIV-positive children aged ≥ 8 years with CD4 ≥ 350 cells/mm³; non-LTNP is defined as antiretroviral-naive, HIV-positive children aged ≥ 8 years with CD4 < 350 cells/mm³; Healthy controls is defined as healthy children aged ≥ 8 years. For lymphocyte subsets, values are expressed in cell count (cells/mm³)