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. 2010 Dec 20;5(12):e15188. doi: 10.1371/journal.pone.0015188

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Yu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Unbiased motif search for GBRs in or nearby glucocorticoid-activated and –repressed genes. A) Bioprospector analysis identified a motif that is highly similar to a consensus GRE in STAMP for glucocorticoid-induced genes. B) Bioprospector and STAMP identified putative motifs for other transcription factors in GBRs of glucocorticoid-activated genes. Top 15 motifs other than GRE were shown. C) Bioprospector analysis identified a motif that matches a consensus ARE in STAMP in glucocorticoid-repressed genes. Notably, the sequences of this consensus ARE is very similar to those of consensus GRE. D) Bioprospector and STAMP identified putative motifs for other transcription factors in GBRs of glucocorticoid-repressed genes. Top 15 motifs other than ARE/GRE were shown.