Figure 1. Syx5 ^+/− Drosophila show increased dietary copper tolerance.

‘Armenia’ and ‘w¹¹¹⁸’ are control strains with normal copper homeostasis mechanisms. ‘DB’ is a double balancer strain containing the CyO balancer chromosome present in the Syx5^+/− mutants. ‘Df(2L)r10’ is an original mapping strain and ‘Syx5^AR113’ is a specific Syx5 null allele. Values are mean with s.e.m. Both Syx5 heterozygous strains show increased copper tolerance compared to the three controls. *Significant difference from Armenia, determined by a Mann-Whitney test (P<0.05). There was no difference in survival between w¹¹¹⁸ and Syx5^AR113/+ flies on concentrations of BCS up to 1 mM (F = 0.778, P = 0.610).