Figure 3. NADPH oxidase subunits are increased in 18–19 day old (pre-necrotic) mdx mice.

A. Representative western blots of all NADPH oxidase subunits from TA muscles of 18–19 day old WT and mdx mice. B. Pooled results from densitometry for the subunits showing mdx values normalized to WT (represented by the blue dotted line). The proteins gp91^phox, p67^phox and rac1 were all significantly increased in mdx muscle compared to WT, whereas p22^phox and p47^phox were not different (n = 4 samples for each group).