Table 1.
Performance on the 5-CSRTT at varying stimulus durations
| Stimulus duration (s) | Number of trials** |
Percentage accuracy** |
Percentage omissions** |
Premature** |
Correct latency (s)** |
Reinforcer latency (s) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | α5−/− | WT | α5−/− | WT | α5−/− | WT | α5−/− | WT | α5−/− | WT | α5−/− | |
| 1.0 | 98.2 ± 1.8 | 100 ± 0.0 | 97.6 ± 0.6 | 97.0 ± 0.9 | 24.3 ± 3.0 | 31.5 ± 3.6 | 1.3 ± 0.4 | 1.0 ± 0.3 | 0.75 ± 0.02 | 0.76 ± 0.03 | 1.45 ± 0.04 | 1.50 ± 0.04 |
| 0.5 | 95.5 ± 2.5 | 96.1 ± 3.0 | 92.4 ± 1.3 | 86.7 ± 2.1 | 36.0 ± 4.5 | 42.1 ± 5.1 | 1.9 ± 0.5 | 3.1 ± 0.9 | 0.61 ± 0.03 | 0.63 ± 0.04 | 1.44 ± 0.05 | 1.56 ± 0.06 |
| 0.25 | 87.4 ± 3.6 | 93.8 ± 3.2 | 79.5 ± 2.8 | 72.3 ± 2.1 | 43.2 ± 3.7 | 47.5 ± 3.0 | 3.8 ± 0.9 | 5.6 ± 1.5 | 0.62 ± 0.04 | 0.70 ± 0.05 | 1.39 ± 0.04 | 1.51 ± 0.06 |
| 0.125 | 78.0 ± 4.8 | 83.8 ± 5.6 | 62.5 ± 2.8 | 54.3 ± 2.5* | 47.3 ± 4.4 | 50.7 ± 2.8 | 7.3 ± 1.1 | 7.5 ± 1.1 | 0.67 ± 0.05 | 0.74 ± 0.05 | 1.44 ± 0.05 | 1.51 ± 0.04 |
Data are presented as mean ± 1 SEM.
*p < 0.05 compared with WT mice at 0.125 s stimulus duration.
**p < 0.001 for an overall effect of stimulus duration. Accuracy measures are also depicted in the graph in Figure 5A.