Table 1. Correlation among clinicopathologic status and the expression of ALDH1, PCNA and apoptosis.
characteristics | Subgroup | ALDH1 | PCNA | AI | ||||||
≤20% | >20% | P | ≤20% | >20% | P | No. | Mean±SD | P | ||
Age | ≤40 years | 51 | 11 | 0.916 | 36 | 26 | 0.227 | 62 | 1.47±0.61 | 0.721 |
>40 years | 103 | 27 | 86 | 44 | 130 | 1.44±0.58 | ||||
ER | Positive | 113 | 26 | 0.541 | 92 | 47 | 0.242 | 53 | 1.41±0.60 | 0.578 |
Negative | 41 | 12 | 30 | 23 | 139 | 1.46±0.59 | ||||
PR | Positive | 96 | 22 | 0.668 | 77 | 41 | 0.359 | 118 | 1.48±0.57 | 0.540 |
Negative | 58 | 16 | 45 | 29 | 74 | 1.43±0.60 | ||||
HER2 | Positive | 21 | 7 | 0.304 | 14 | 14 | 0.102 | 28 | 1.45±0.59 | 0.727 |
Negative | 133 | 31 | 108 | 56 | 164 | 1.41±0.59 | ||||
Clinical Stage | II | 114 | 6 | <0.001 | 96 | 24 | <0.001 | 120 | 1.50±0.52 | 0.116 |
III | 40 | 32 | 26 | 46 | 72 | 1.37±0.67 | ||||
Grade | I | 15 | 1 | <0.001 | 13 | 3 | 0.145 | 16 | 1.39±0.52 | 0.834 |
II | 86 | 32 | 64 | 45 | 109 | 1.44±0.59 | ||||
III | 14 | 53 | 45 | 22 | 67 | 1.48±0.61 | ||||
Tumor size | T1 | 31 | 0 | <0.001 | 31 | 0 | <0.001 | 31 | 1.65±0.40 | <0.001 |
T2 | 102 | 15 | 82 | 35 | 117 | 1.51±0.55 | ||||
T3 | 21 | 23 | 9 | 35 | 44 | 1.14±0.70 | ||||
Node Metastasis | 1–3 | 131 | 23 | <0.001 | 106 | 48 | 0.013 | 154 | 1.52±0.51 | 0.030 |
≥4 | 22 | 14 | 16 | 22 | 38 | 1.35±0.67 |
ALDH1 = aldehyde dehydrogenase 1; AI = apoptotic index, percentage of apoptotic cancer cells.