Table 4. Associations between the ALOX5 gene and CD in Canadian children.
SNP | Model | Cases | Controls | P-value |
rs2115819 (C/T) | TREND | 394/444 | 437/535 | 0.39 |
DOM | 296/123 | 334/152 | 0.53 | |
REC | 98/321 | 103/383 | 0.43 | |
rs3780901 (C/T) | TREND | 256/592 | 324/652 | 0.17 |
DOM | 213/211 | 276/212 | 0.056 | |
REC | 43/381 | 48/440 | 0.88 | |
rs2291427 (A/G) | TREND | 249/599 | 314/662 | 0.20 |
DOM | 209/215 | 264/224 | 0.15 | |
REC | 40/384 | 50/438 | 0.68 | |
rs10751383 (A/C) | TREND | 349/495 | 435/541 | 0.17 |
DOM | 273/149 | 337/151 | 0.16 | |
REC | 76/346 | 98/390 | 0.43 |
DOM: dominant, REC: recessive, TREND: Cochran-Armitage trend test. For this test, the numbers in the table represent the number of chromosomes that had the minor or the major allele.