Table 1.
Variable | Control, n = 35 | Schizophrenia, n = 35 | Bipolar disorder, n = 34 |
---|---|---|---|
Demographic | |||
Age at death, mean (SD) yr | 44.2 (7.6) | 42.6 (8.5) | 45.4 (10.7) |
Sex, male:female | 26:9 | 26:9 | 16:18† |
Postmortem characteristic | |||
Postmortem interval, mean (SD) h | 29.4 (12.9) | 31.4 (15.5) | 37.9 (18.6) |
Brain pH, mean (SD) | 6.6 (0.3) | 6.5 (0.2) | 6.4 (0.3)† |
Brain hemisphere, right:left | 16:19 | 17:18 | 19:15 |
Clinical | |||
Cause of death | |||
Cardiopulmonary | 33 | 21 | 7 |
Suicide | 7 | 15 | |
Other | 2 | 7 | 12 |
Age at onset, mean (SD) yr | — | 21.3 (6.1) | 25.3 (9.2) |
Duration of disorder, mean (SD) yr | — | 21.29 (10.15) | 20.15 (9.462) |
Antipsychotic dose, median (range) mg* | — | 48000 (50–400000) | 3000 (0–13000) |
Alcohol history, none/mild:moderate or heavy past or present use | 30:5 | 17:18 | 12:21 (1 missing) |
Drug history, none/mild:moderate or heavy past or present use | 35:0 | 18:15 (2 missing) | 15:19 |
SD = standard deviation.
Antipsychotic dose is lifetime dose in chlorpromazine milligram equivalents.
p < 0.05, statistically significant differences between the psychiatric and control groups.