. Author manuscript; available in PMC: 2011 Dec 15.

Published in final edited form as: Clin Cancer Res. 2010 Sep 27;16(24):6139–6149. doi: 10.1158/1078-0432.CCR-10-0978

Table 3.

Detection of Gold Nanoparticles in Normal and Neoplastic Tissues from Subjects Treated with Various Doses of CYT-6091. (ND=not determined)

Dose (μg/m²)	Patient ID	Diagnosis	Site of Biopsy	Normal Tissue		Tumor Tissue
Dose (μg/m²)	Patient ID	Diagnosis	Site of Biopsy	Particles	Fields	Particles	Fields
50	0601-01	Cutaneous Melanoma	Chest Wall	10	10	91	6
	0601-02	Colon Adenocarcinoma	Liver	2	6	13	11
	0601-03	Ocular Melanoma	Liver	0	4	5	11
100	0601-04	Colon Adenocarcinoma	Liver	0	5	13	10
	0601-05	Colon Adenocarcinoma	ND	-	-	-	-
	0601-06	Ocular Melanoma	Scalp	1	7	0	7
150	0601-07	Lung Adenocarcinoma	Liver	0	6	33	5
	0601-08	Pancreatic Adenocarcinoma	Liver	0	6	135	12
	0601-09	Pancreatic Adenocarcinoma	Liver	2	5	0	5
200	0601-10	Invasive Ductal Carcinoma	Breast	0	5	167	5
	0601-11	Leiomyosarcoma	Muscle	3	4	31	10
	0601-12	Ocular Melanoma	Liver	7	6	8	10
250	0601-13	Ocular Melanoma	Muscle	19	7	0	4
	0601-15	Pancreatic Adenocarcinoma	Liver	1	5	4	7
	0601-16	Ocular Melanoma	Liver	0	5	0	5
300	0601-17	Colon Adenocarcinoma	ND	-	-	-	-
	0601-18	Ocular Melanoma	Liver	8	10	16	12
	0601-19	Ocular Melanoma	Liver	15	6	5	5
	0601-20	Ocular Melanoma	Liver	23	6	0	6
400	0601-21	Desmoplastic Small Round Cell	Omentum	0	5	0	6
	0601-22	Rectal Adenocarcinoma	Liver	27	7	10	5
	0601-23	Colorectal Adenocarcinoma	Liver	78	6	0	5
500	0601-24	Ocular Melanoma	Skin	0	8	1	9
	0601-25	Invasive Ductal Carcinoma	Liver	148	9	0	7
	0601-26	Colorectal Adenocarcinoma	ND	-	-	-	-
600	0601-27	Desmoplastic Small Round Cell	ND	-	-	-	-
	0601-28	Colorectal Adenocarcinoma	ND	-	-	-	-
	0601-29	Colorectal Adenocarcinoma	ND	-	-	-	-
	0601-30	Adenocarcinoma	ND	-	-	-	-