Table I.
Number of deaths due to varicella infection among 35,128 children with acute lymphoblastic leukemia
| Group | Protocol | Country | Period | No. Patients | No. Deaths | |
|---|---|---|---|---|---|---|
| 1 | AIEOP | 91, 95 and 2000 | Italy | 1991–2008 | 4934 | 3 |
| 2 | SJCRH | Total XI–XV | USA | 1984–2007 | 1512 | 1 |
| 3 | INS | INS-1989, 2003 | Israel | 1989–2007 | 628 | 3 |
| 4 | Czech Rep | 95, 2002 | Czech Republic | 1996–2007 | 690 | 0 |
| 5 | COALL | COALL92-97 | Germany | 1992–2003 | 1188 | 0 |
| 6 | BFM | ALL-2000 | Germany | 2000–2008 | 3500 | 7 |
| 7 | JACLS | 97 and 02 | Japan | 1997–2006 | 1612 | 1 |
| 8 | TCCSG | 92, 95 and 99 | Japan | 1992–2003 | 1698 | 0 |
| 9 | KYCCSG | ALL02 | Japan | 2002–2007 | 165 | 1 |
| 10 | DCOG | 8, 9 and 10 | The Netherlands | 1991–2008 | 1656 | 2 |
| 11 | POG | Various | North America | 1990–2005 | 8746 | 2 |
| 12 | NOPHO | ALL-92; ALL-2000 | Nordic Countries | 1992–2006 | 2668 | 0 |
| 13 | FRALLE | FRALLE 93, 2000 A + BT | France | 1993–2008 | 3424 | 0 |
| 14 | TPOG | ALL-97; ALL-2002 | Taiwan | 1997–2008 | 1407 | 0 |
| 15 | DFCI | DFCIC-Protocol 95 | North America | 1996–2008 | 1300 | 0 |
| TOTAL | 35,128 | 20 | ||||
Abbreviations: AIEOP, Associazione Italiana di Ematologia ed Oncologia Pediatrica; SJCRH, St. Jude Children’s Research Hospital; INS, Israel National Studies; COALL, Cooperative Acute Lymphoblastic Leukemia Study Group; BFM, Berlin-Frankfurt-Münster Group; JACLS, Japan Association of Childhood Leukemia Study; TCCSG, Tokyo Children’s Cancer Study Group; KYCCSG, Kyushu Yamaguchi Children’s Cancer Study Group; DCOG, Dutch Childhood Oncology group; POG, Pediatric Oncology group; NOPHO; Nordic Society for Paediatric Haematology-Oncology; FRALLE, French Acute Lymphoblastic Leukemia Study Group; TPOG, Taiwan Pediatric Oncology Group; DFCI, Dana-Farber Cancer Institute.