Figure 2. In vivo pretreatment with ψεRACK reduces cerebral reperfusion after ischemia.
A ψεRACK bolus 30 min before cerebral ischemia reduced post-ischemic cerebral blood flow (CBF). CBF (% of baseline) curves of laser-Doppler flowmetry tracing before, during, and one hour after an ischemic insult produced by bilateral carotid occlusion and systemic hypotension. P<0.05 compared to Tat peptide.