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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Bioconjug Chem. 2010 Feb 4;21(3):436–444. doi: 10.1021/bc9003102

Figure 4.

Figure 4

Comparison of Cy5.5 and 64Cu tissue biodistribution. The amount of (A) DOTA/Cy5.5-2.5D or (B) 64Cu-DOTA/Cy5.5-2.5D accumulation was measured in the blood (Bl), heart (H), liver (Li), lung (Lu), muscle (M), spleen (Sp), brain (Br), tumor (T), skin (Sk), pancreas (P), and bone (Bn). (A) Cy5.5 uptake, measured as the fluorescence flux (photons per second) per gram of tissue. (B) 64Cu uptake, quantified as the %ID/g. Comparison of Tumor/Tissue ratios observed at 1, 4, and 24 hr post injection for (C) DOTA/Cy5.5-2.5D or (D) 64Cu-DOTA/Cy5.5-2.5D.