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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Ann Hum Genet. 2010 Oct 26;75(1):105–111. doi: 10.1111/j.1469-1809.2010.00615.x

Table 2.

Relative efficiencies for Model A under various r2 combinations and allele frequencies. The first column shows the r2 values between the causal and tag SNPs. Various combinations of allele frequencies are investigated. Each entry of the table gives the ratio of sample sizes that lead to the same power. All results are based on 2000 repetitions.

Allele Frequencies

( r12,r22)
r12×r22
Power (0.5,0.4) (0.5,0.3) (0.5,0.2) (0.4,0.3) (0.4,0.2) (0.3,0.2)

(0.9,0.9) 0.81 0.3 0.771 0.762 0.760 0.775 0.772 0.761
0.6 0.785 0.791 0.790 0.783 0.789 0.772
0.9 0.794 0.787 0.783 0.774 0.794 0.792

(0.9,0.7) 0.63 0.3 0.589 0.614 0.669 0.610 0.639 0.655
0.6 0.602 0.603 0.642 0.617 0.649 0.668
0.9 0.581 0.615 0.661 0.620 0.67 0.668

(0.9,0.5) 0.45 0.3 0.411 0.465 0.500 0.432 0.505 0.535
0.6 0.413 0.443 0.511 0.445 0.531 0.531
0.9 0.415 0.449 0.507 0.458 0.521 0.549

(0.7,0.7) 0.49 0.3 0.439 0.47 0.467 0.486 0.483 0.518
0.6 0.452 0.443 0.473 0.478 0.486 0.523
0.9 0.440 0.466 0.474 0.464 0.503 0.503

(0.7,0.5) 0.35 0.3 0.310 0.316 0.363 0.353 0.389 0.410
0.6 0.305 0.322 0.373 0.347 0.398 0.409
0.9 0.313 0.331 0.393 0.336 0.390 0.422

(0.5,0.5) 0.25 0.3 0.217 0.233 0.259 0.241 0.261 0.310
0.6 0.216 0.233 0.262 0.241 0.274 0.297
0.9 0.218 0.235 0.266 0.241 0.269 0.300