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. Author manuscript; available in PMC: 2011 Aug 11.
Published in final edited form as: Structure. 2010 Aug 11;18(8):955–965. doi: 10.1016/j.str.2010.04.017

Figure 7. Model Structure of E4B, UbcH5c and Ubiquitin Ternary Complex.

Figure 7

The structures of budding yeast Ufd2 (aa 188-961 from PDB entry 2QIZ), human UbcH5c–ubiquitin (PDB entry 2FUH) and human E4B U-box–UbcH5c (this study) were superimposed to model the complex. Ubiquitin (yellow), UbcH5c (gray) and Ufd2 (body in green and U-box in blue) fit together in the model with very few steric clashes and leave the active site cysteine of UbcH5c (red) accessible to react with a ubiquitin molecule.