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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Jul 23;49(4):587–597. doi: 10.1016/j.yjmcc.2010.07.010

Figure 4.

Figure 4

Apoptotic cell death is increased in AMD3100-treated mice after infarction. Apoptotic cell death was assessed in Vehicle- and AMD3100- treated hearts after ligation and sham surgery by TUNEL staining. (A) Representative fluorescent confocal images of TUNEL stained apoptotic nuclei from vehicle- and AMD3100-treated mice after ligation or sham surgery. (B) TUNEL staining and apoptotic cell death is increased in the LV of AMD3100-treated hearts after ligation. (C) Apoptotic cell death was predominant in the risk region of AMD treated hearts after ligation. Arrows denote apoptotic nuclei. Values are mean ± SEM (n=6-8). *P<0.05 vs Vehicle Ligation.