Figure 7. Characterization of binding interactions between mouse IL-13Rα2 domain D2 and IL-13 using peptide array analysis.
(A) Structure of the complex and enlarged view showing the interactions between domain D2 of mIL-13Rα2 (white) and IL-13. The electrostatic potential at the molecular surface of IL-13 is shown (blue, positive; red, negative; white, neutral) and residues identified using peptide arrays are highlighted on domain D2 of mouse IL-13Rα2. (B) The bar chart represents fluorescence reference units corresponding to overlapping peptide sequences from domain D2 of mIL-13Rα2.