Table 2.
Peptide Sequences Selected from Peptide Library against HDAC6 BUZ Domaina
| Class I | Class II | MVRHH | KRYAR | RGYRR |
| HHQGG | DDGMF | WKWIH | NALER | WNGGY |
| FRAGG | FEDGM | LRPKH | IRIFR | RREHY |
| RYUGG | WADGY | HRWLH | VMPGR | RIHKY |
| FKUGG | ADGMY | UKQRH | SRUHR | WKALY |
| RKDGG | FLRSH | AWHHR | YGHPY | |
| QREGG | Class III | RHIWH | YYHHR | DIAYR |
| RCEGG | SHPQU | RTTWH | GYMHR | MIKRY |
| RSEGG | SHPQF | RFQYH | VIRHR | RFQRY |
| WUFGG | HPQXX | YIYAI | QVRHR | LIKYY |
| WYHGG | HPQXX | THMDI | FKWHR | MYYYY |
| HAHGG | HPQXX | WVYGI | RYDIR | |
| VKHGG | WHPQG | VLRHI | RQLLR | |
| WMHGG | VVGLI | RVTLR | ||
| HEIGG | Class IV | IWIMI | LRUMR | |
| YLIGG | HSHIH | LFFQI | VRSMR | |
| XXKGG | FRHYH | IFEYI | WSARR | |
| LHKGG | YHKHT | YRHFK | RYFRR | |
| HDKGG | HKHYW | URQKK | LKGRR | |
| TRKGG | HRHPY | PGNDL | LLHRR | |
| AFKGG | HRHXX | QTVFL | AGIRR | |
| LLKGG | HTHRR | QLVLL | RIQRR | |
| IKKGG | HIHRR | IMAQL | KFYRR | |
| XXKGG | HAHXX | IYFQL | LRATR | |
| RNKGG | YHDHV | WWHRL | YHNTR | |
| REKGG | RKQRL | GIRVR | ||
| NALGG* | Class V | LSMSL | QHPWR | |
| RVLGG | LSGPA | FHKVL | QRUYR | |
| HTLGG | ETWUU | MNWFM | FKFFS | |
| EGLGG | WRIFU | IRHHM | MLMGS | |
| DHLGG | WMQFU | YEALM | MUITS | |
| QELGG | RRWNU | FQULM | FLLAT | |
| FTMGG | WMEPD | KPMLM | HPVHT | |
| RRMGG | MFNMD | KGPQM | YRRQT | |
| MYMGG | RWHAF | RVSQM | LRLRT | |
| WWMGG | LELAF | KIQRM | NNMTT | |
| FNMGG | YRRFF | LURRM | IFLYT | |
| HWPGG | RRAGF | TLUSM | LUEHV | |
| NYPGG | MYRHF | DVHTM | UYRHV | |
| SWPGG | MSRHF | RMHVM | KIYKV | |
| MIQGG | UHHKF | IYWYM | FSIRV | |
| LLQGG | EYFLF | HIYYM | AKDWV | |
| IRQGG | RHGLF | VVDQP | RHGRW | |
| ULQGG | GIILF | GLRVP | HUUWW | |
| UMRGG | MPVLF | RQFRQ | RRUWW | |
| RFSGG | SRHMF | TILTQ | UTYWW | |
| QRWGG | LAKMF | YRRWQ | LQIHA | |
| YIWGG | TRSRF | SRRWQ | MYRER | |
| HHYGG | LYUIG | SWRAR | YFRRU | |
| FYYGG | ADSIG | SLRAR* | QVRRL | |
| HVYGG | LRUMG | WQKAR | WWHLR |
a
M, norleucine; U, (S)-2-aminobutryic acid; X, amino acids whose identity could not be unambiguously determined.
*
sequences selected for resynthesis and binding analysis.