TABLE 3. Proliferative responses vs. histology.
Liver biopsy | Days in culture | Proliferative responses (CPM ± S.D.) | Cause of graft dysfunction | ||
---|---|---|---|---|---|
Background | Exogenous IL-2 | Donor stimulated | |||
1.7A | 12 | 452 ± 62 | 19,581 ± 1,536 | 27,472 ± 2,741 | moderate rejection |
3.32A | 14 | 2,097 ± 1,608 | 13,413 ± 1,395 | 17,120 ± 1,119a | mild rejection |
5.300B | 12 | 825 ± 92 | 8,614 ± 365 | 9,404 ± 1,466 | mild rejection |
6.73A | 10 | 303 ± 65 | 15,870 ± 908 | 16,223 ± 827a | severe rejection |
7.5A | 14 | 858 ± 114 | 11,867 ± 1,453 | 9,334 ± 1,757 | moderate rejection |
8.9A | 9 | 708 ± 60 | 2,556 ± 50 | 4,008 ± 380 | severe rejection |
8.13A | 7 | 916 ± 191 | 15,215 ± 71 | 27,738 ± 1,989 | moderate rejection |
9.9A | 12 | 222 ± 23 | 7,730 ± 306 | 1,8941 ± 959 | severe rejection |
9.11B | 12 | 2,210 ± 335 | 34,678 ± 1,556 | 22,896 ± 1,900 | moderate rejection |
9.39B | 8 | 1,211 ± 152 | 9,299 ± 93 | 21,547 ± 1,544a | severe rejection |
10.59B | 4 | 614 ± 194 | 30,713 ± 1,209 | 18,067 ± 911 | severe rejection |
13.5A | 10 | 939 ± 75 | 14,981 ± 884 | 8,448 ±115 | early rejection? |
13.28B | 7 | 4,447 ± 194 | 55,395 ± 1,694 | 125,294 ± 1,972 | ischemic injury |
2.16A | 21 | 257 ± 35 | 10,189 ± 744 | 2,774 ± 1,119a | ischemic injury |
4.12A | 10 | 411 ± 112 | 8,536 ± 170 | 728 ± 117 | mild rejection |
11.3A | 15 | 1,118 ± 11 | 24,420 ± 606 | 2,690 ± 1,454 | ischemic injury |
12.3A | 18 | 631 ± 145 | 25,755 ± 3,149 | 865 ± 442 | yeast infection |
14.30A | 21 | 187 ± 5 | 9,775 ± 15 | 593 ± 64 | moderate rejection |
Donor cell not available, maximum stimulation with panel cell.