Table 2.
Parameter | Concentration (mean ± S.E.) in group† | |||||||
---|---|---|---|---|---|---|---|---|
Control diet | Magnesium carbonate‐containing diet | Lanthanum carbonate‐containing diet | ||||||
lm → 3m | lm → 6m | lm → 3m | lm → 6m | 3m → 6m | lm → 3m | lm → 6m | 3m → 6m | |
Calcium (mg/dL) | 10.70 ± 0.69 | 11.54 ± 0.42 | 10.94 ± 0.30 | 12.72 ± 0.62 | 10.95 ± 0.28 | 11.25 ± 0.32 | 11.26 ± 0.22 | 11.27 ± 0.11 |
Phosphorus (mg/dL) | 14.29 ± 1.87 | 15.55 ± 1.38 | 16.03 ± 0.50 | 16.28 ± 0.95 | 13.59 ± 1.89 | 15.72 ± 0.23 | 15.46 ± 0.91 | 13.98 ± 1.28 |
Ca/P ratio | 0.75 ± 0.06 | 0.78 ± 0.08 | 0.68 ± 0.02 | 0.78 ± 0.02 | 0.91 ± 0.11 | 0.72 ± 0.02 | 0.74 ± 0.05 | 0.84 ± 0.06 |
Magnesium (mg/dL) | 3.07 ± 0.31 | 3.11 ± 0.14 | 3.00 ± 0.12 | 3.94 ± 0.18‡ | 3.06 ± 0.21 | ND | ND | ND |
*Abcc6 −/− mice at 1 or 3 months of age were placed on different diets. Serum concentrations of calcium, phosphorus and magnesium were determined at either 3 or 6 months of age.
† Statistical significance in comparison to the Abcc6 −/− mice on control diet is indicated: ‡ p < 0.05 (n= 5–9).
ND = not determined.