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. Author manuscript; available in PMC: 2010 Dec 21.
Published in final edited form as: Chem Res Toxicol. 2008 May 1;21(6):1205–1210. doi: 10.1021/tx800012p

Fig. 1. Cells with increased Trx2 level were more sensitive to NEM toxicity.

Fig. 1

(A) 143 B cells transfected with empty vector or Trx2 were exposed to different concentrations of NEM for 2 h. Cells were then harvested and the viability was measured by flow cytometry. (B) Cells were treated with 30 μM of NEM and the viability was measured at the indicated time points. (C) Cells were treated with different concentrations of NEM for 1 h and intracellular GSH were measured by HPLC. Results are the average of three separate experiments (mean ± SEM).