Figure 7. Suppression of SOX10 inhibits the proliferation of Notch4-immortalized cells.
Notch4-immortalized cells were transfected with two siRNAs targeting SOX10 (siSOX1 and siSOX2) or control siRNA (siNS). (A) The suppression of SOX10 was demonstrated by real-time PCR. (B) The cells (1×104) were plated and counted at indicated time points after initial seeding. The cells expressing siRNAs against SOX10 proliferated slower than cells expressing control siRNA (P < 0.01).