Table 2.
Doses (mg/kg body weight) | ||||
Parameters | Control | 50 | 100 | 200 |
Liver body weight ratio (%) |
4.20±0.13a | 4.32±0.86a | 4.20±0.11a | 4.19±0.36a |
Total protein (g L−1) | 68.00±1.22a | 69.40±4.50a | 70.60±2.19a | 69.80±1.64a |
Albumin (mmol L−1) | 17.80±0.44a | 18.00±1.00a | 18.80±1.09a | 15.40±1.51b |
Globulin (mmol L−1) | 50.60±1.34a | 51.40±3.50a | 51.80±3.03a | 54.40±0.89b |
Total bilirubin (mmol L−11) | 7.40±0.54a | 8.80±3.03a | 8.40±1.51a | 15.40±4.72b |
Conjugated bilirubin | 2.40±0.54a | 2.40±0.54a | 2.30±0.02a | 6.40±0.88b |
(umol L−1) | ||||
Kidney body weight ratio | 0.78±0.12a | 0.80±0.11a | 0.76±0.04a | 0.79±0.06a |
(%) | ||||
Sodium (mmol L−1) | 140.20±1.30a | 141.00±1.87a | 141.80±0.44a | 141.00±1.00a |
Potassium (mmol L−1) | 5.22±0.25a | 5.20±0.18a | 5.28±0.32a | 6.18±0.57b |
Chloride (mmol L−1) | 103.80±1.30a | 105.40±1.67a | 104.00±1.87a | 103.40±0.54a |
Inorganic phosphorus | 3.06±0.11a | 2.86±0.21a | 3.14±0.08a | 3.78±0.21b |
(mmol L−1) | ||||
Urea (mmol L−1) | 6.96±0.1ba | 8.70±1.39b | 8.50±1.23b | 6.22±0.08a |
Creatinine (mmol L−1) | 44.00±2.34a | 44.80±4.76a | 34.40±7.70b | 37.60±7.23ba |
Alkaline phosphatase | 328.40±12.45a | 345.40±7.49a | 349.40±6.43a | 343.40±4.72a |
(U/L) | ||||
Gamma glutamyl | 5.00±0.00a | 5.80±1.30a | 5.60±1.34a | 5.00±0.00a |
transferase (U/L) | ||||
Alanine aminotransferase | 54.80±5.97ba | 52.40±3.71b | 56.60±8.32ba | 53.20±4.00a |
(U/L) | ||||
Aspartate | 209.80±9.71a | 200.40±8.39a | 193.4±14.56a | 248.00±8.68b |
aminotransferase (U/L) |
Means with the same superscripts as control across the rows are not significantly different (p>0.05)