Table 3.
Plasma antibodies against oxidized epitopes in 8 wk mice
Antibody specificity | Antibody class | PBS, n = 5 | 4F, n = 5 | Pro, n = 8 |
---|---|---|---|---|
MDA-LDL | IgM | 235.43 ± 19.2 | 287.22 ± 26.1* | 242.77 ± 37.3 |
IgG | 35.03 ± 26.9 | 17.38 ± 12.8 | 19.17 ± 3.7 | |
Cu-oxLDL | IgM | 101.81 ± 33.0 | 249.85 ± 20.0* | 162.08 ± 52.6* |
IgG | 1.29 ± 0.2 | 4.49 ± 0.6* | 3.0 ± 1.0* | |
E06/T15 | IgM | 25.7 ± 32.1 | 251.32 ± 6.0* | 165.0 ± 76.3* |
Plasma total IgM | 149.95 ± 38.8 | 143.22 ± 15.5 | 119.73 ± 25.9 | |
Plasma total IgG | 21.43 ± 12.2 | 29.45 ± 5.4 | 43.51 ± 12.6* |
Values are average ± sd luminescence (103 RLU/100 ms); intratiter comparisons.
P < 0.05 vs. PBS treatment.