Table 1.

Differences between wild-type and Ccr2^−/− mice during acute muscle injury repair

Genotype	Inflammation	Phagocytosis	Regeneration	IGF-1 production
Wild type	Large peak at d 3	Efficient at d 5 and 7	Active at d 5 and 7; regenerated well by d 21 and 42	Large peak at d 3
Ccr2−/−	Small peak at d 7; ↓Ly-6C+ MOs/MPs in PB and IM; ↓Ly-6C− MOs/MPs in IM	Impaired at d5 and d7	Impaired at d 5 and 7; small regenerated fibers by d 21 and 42	Small peak at d 7

PB, peripheral blood; IM, injured muscle.