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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Atherosclerosis. 2010 Aug 19;214(1):58–64. doi: 10.1016/j.atherosclerosis.2010.08.054

Figure 3. GX sPLA2 deficiency reduces atherosclerosis in Ang II-infused apoE−/− mice.

Figure 3

Male apoE−/− and GX DKO mice were infused with 1,000 ng kg−1 min−1 Ang II for 28 days. (A) Atherosclerotic lesion area in the aortic root. Values are mean lesion areas (± SE) per section for sections ~64 μm apart (n = 4). The transition zone between the aortic sinus and the ascending aorta, de ned by disappearance of the valve cusps, is 0 on the x-axis. (B) Atherosclerotic lesion area quantified on the luminal surface of the aortic arch. Values are mean % lesion area (± SE; n = 17–18). **, p < 0.01.