Table.
Patient and Tumor Characteristics: Pediatric and Adult Patients With Squamous Cell Carcinoma of the Oral Surface of the Tonguea
| Variable | Pediatric (n=10) | Adult (n=40) | P Value |
|---|---|---|---|
| Sex | |||
| Male | 2 (20) | 8 (20) | .99 |
| Female | 8 (80) | 32 (80) | |
| Tobacco history | |||
| Yes | 1 (11) | 18 (53) | .06 |
| Never | 7 (78) | 16 (47) | |
| Alcohol history | |||
| Yes | 2 (22) | 12 (57) | .12 |
| Never | 7 (78) | 9 (43) | |
| Clinical T stage | |||
| T1 | 3 (30) | 12 (30) | .99 |
| T2 | 4 (40) | 16 (40) | |
| T3 | 3 (30) | 12 (30) | |
| T4 | 0 | 0 | |
| Clinical N stage | |||
| N0 | 7 (70) | 28 (70) | .97 |
| N1 | 2 (20) | 6 (15) | |
| N2 | 1 (10) | 6 (15) | |
| N3 | 0 | 0 | |
| Clinical M stage | |||
| M0 | 10 (100) | 40 (100) | .99 |
| M1 | 0 (0) | 0 (0) | |
| Depth of invasion, mm | |||
| <5 | 1 (20) | 7 (21) | .57 |
| ≥5 | 4 (80) | 27 (79) | |
| Histologic grade | |||
| Well differentiated | 3 (30) | 9 (26) | .63 |
| Moderately differentiated | 7 (70) | 23 (66) | |
| Poorly differentiated | 0 (0) | 3 (9) | |
| Margin status | |||
| Positive/close | 3 (33) | 4 (10) | .23 |
| Negative | 6 (67) | 34 (89) | |
| Perineural invasion | |||
| Yes | 2 (50) | 33 (85) | .31 |
| No | 2 (50) | 6 (15) | |
| Vascular invasion | |||
| Yes | 0 | 1 (3) | .16 |
| No | 4 (100) | 38 (97) | |
| Treatment modality | |||
| Surgery | 5 (50) | 20 (50) | .99 |
| Surgery + RT | 5 (50) | 20 (50) | |
| Neck treatment | |||
| Neck dissection | 10 (100) | 40 (100) | .99 |
| No neck dissection | 0 | 0 | |
Abbreviation: RT, radiotherapy.
a
Data are given as number (percentage).