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. Author manuscript; available in PMC: 2010 Dec 21.
Published in final edited form as: Am J Transplant. 2009 May;9(5):1037–1047. doi: 10.1111/j.1600-6143.2009.02619.x

Table 3.

T-cell subsets from the peripheral blood in recipients with stable mixed hematopoietic chimerism: Effect of lung transplantation#

Peripheral Blood Normal (n=10) Mean % (SD) MC (n=10) Mean % (SD) MC/Lung (n=4) Mean % (SD) P-value Normal vs. MC P-value Normal vs. MC/Lung P-value MC vs. MC/Lung
* CD8 INFγ 17.0 (4.8) 21.2 (9.4) 33.5 (4.2) 0.23 <0.0001 0.03
+ CD4 INFγ 12.6 (4.2) 19.4 (7.4) 29.5 (6.5) 0.02 <0.0001 0.04
CD4 TNFα 7.6 (5.0) 9.7 (5.1) 11.7 (3.8) 0.38 0.17 0.50
+ CD4 IL-4 1.3 (1.1) 4.2 (2.7) 10.1 (4.8) 0.006 <0.0001 0.01
+ CD4 IL-10 1.7 (0.6) 1.7 (0.8) 2.1 (0.8) 0.99 0.30 0.37

Footnotes: IL-4 = interleukin 4; IL-10 = interleukin 10; INFγ = interferon gamma; MC = mixed chimerism; MC/Lung = mixed chimerism + lung transplantation; SD = standard deviation; TNFα = tumor necrosis factor alpha.

#

All recipients and normal dogs had T cell subsets from the peripheral blood assessed at least twice. Transplant recipients were assessed while the grafts and clinical status were stable.

*

CD3+CD8+INFγ+ T cells are given as a percentage of the total number of CD3+CD8+ T cells.

+

CD3+CD4+ T cell subsets are given as a percentage of the total number of CD3+CD4+ T cells.