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. Author manuscript; available in PMC: 2010 Dec 21.
Published in final edited form as: Nat Med. 1996 Feb;2(2):163–165. doi: 10.1038/nm0296-163

Fig. 2.

Fig. 2

upper panels, One-way paradigm in which transplantation is conceived as involving a unidirectional immune reaction: host-versus-graft (HVG) with whole-organ transplants (a) and graft-versus-host (GVH) with bone marrow transplants (b). lower panels, Two-way paradigm in which transplantation is seen as a bidirectional and mutually canceling immune reaction that is predominantly HVG with whole-organ grafts (c), and predominantly GVH with bone marrow grafts (d).