Table 3.
Genetic effects that replicated, cross-validated, and passed false discovery rate criterion in female African–American (outcome: diastolic blood pressure; all associations adjusted for age and antihypertensive medications)
Main effects | SNP | Subset 1, P | Subset 2, P | Full sample, P | R2 | CV R2 |
---|---|---|---|---|---|---|
ATP6B1_rs2266917 | 0.0929 | 0.0656 | 0.0018 | 0.0128 | 0.0051 |
SNP–covariate interactions | SNP | Covariate | Subset 1, P | Subset 2, P | Full sample, P | R2 | CV R2 |
---|---|---|---|---|---|---|---|
MMP3_rs679620 | BMI | 0.0506 | 0.0848 | 0.0009 | 0.0141 | 0.0082 | |
MMP3_rs679620 | Waist circumstance | 0.0535 | 0.0849 | 0.0012 | 0.0135 | 0.0080 |
CV R2, cross-validated R2; SNP, single nucleotide polymorphism.