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. 2010 Aug 26;19(11):2110–2121. doi: 10.1002/pro.491

Figure 1.

Figure 1

Functional hot spots and experimentally characterized nsSNPs mapped to the nucleotide binding domain (NBD) sequences of human MRP4. The previously identified nucleotide-binding loop and the ABC signature motif are indicated in black. C-loop 1, the ARA motif, and C-loop 2 are indicated in blue. Experimentally characterized nsSNPs, G487E and K498E (NBD1), and V1071I (NBD2) are indicated in red.