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Dissociation Constants for Fluorescent PRMT1 and PRMT6 with and without Cofactor
| Enzyme | Cofactor | KD (nM)a |
|---|---|---|
| PRMT1 | — | 110 (26) |
| PRMT1 | AdoMet | 30 (14) |
| PRMT1 | AdoHcy | 110 (38) |
| PRMT6 | — | 210 (34) |
| PRMT6 | AdoMet | 180 (104) |
| PRMT6 | AdoHcy | 1100 (67) |
Numbers in parentheses represent standard deviations.
