Table 4.
Case–control comparison of mean HTLDs
| Chromosome arms | All subjects |
Pre-menopausal women |
Post-menopausal women |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases, n = 204 | Controls, n = 236 | P-value | Cases, n = 89 | Controls, n = 96 | P-value | Cases, n = 110 | Controls, n = 132 | P-value | |
| 5q | 38.5 (7.6) | 36.2 (6.9) | 0.006 | 39.4 (7.6) | 35.6 (7.1) | 0.003 | 37.9 (7.5) | 36.6 (6.7) | 0.21 |
| Xp | 38.3 (7.9) | 37.2 (7.3) | 0.09 | 39.4 (8.3) | 36.4 (6.4) | 0.010 | 37.6 (7.7) | 37.9 (7.9) | 0.98 |
| 8q | 40.7 (8.0) | 38.5 (7.8) | 0.010 | 40.9 (7.8) | 38.0 (7.0) | 0.013 | 40.8 (8.2) | 38.9 (8.4) | 0.11 |
| 9p | 38.9 (7.6) | 37.1 (7.6) | 0.015 | 39.1 (7.4) | 35.9 (7.2) | 0.0005 | 38.9 (7.8) | 38.1 (7.7) | 0.65 |
| 12p | 38.8 (7.7) | 36.9 (7.5) | 0.016 | 39.8 (8.2) | 36.5 (7.5) | 0.009 | 38.2 (7.3) | 37.3 (7.5) | 0.46 |
| 15p | 38.9 (7.4) | 38.2 (7.9) | 0.30 | 40.1 (7.8) | 35.9 (7.1) | 9 × 10−5 | 38.1 (7.1) | 40.0 (8.1) | 0.04 |
| 15q | 38.1 (7.4) | 36.5 (7.7) | 0.021 | 38.2 (7.6) | 34.9 (7.5) | 0.003 | 38.2 (7.3) | 38.0 (7.5) | 0.74 |
HTLD was defined as the percent of (homologous long RTL − homologous short RTL) divided by (homologous long RTL + homologous short RTL). Mean (SD)s were presented in the table. P-values were based on Wilcoxon's rank-sum test. Bold P-values are significant after adjustment for multiple comparisons (Bonferroni's correction 0.05/(46 × 2) = 0.0005).