Table 1.
Comparison of ADHOC to Competing Clustering Methods for DIP Yeast PPI Dataset
| Method | Cluster Number | Cluster Size | Discard (%) | GO (-log P-value) | ||
|---|---|---|---|---|---|---|
| MF | BP | CC | ||||
| ADHOC | 50 | 20.56 | 68.05 | 5.18 | 7.44 | 6.38 |
| Maximal Clique | 376 | 4.55 | 80.06 | 3.43 | 4.02 | 2.67 |
| IPCA | 253 | 4.64 | 80.39 | 3.61 | 4.09 | 2.89 |
| DPClus | 90 | 5.27 | 84.49 | 3.91 | 4.50 | 3.44 |
| MCODE | 29 | 23.76 | 75.21 | 4.20 | 5.23 | 4.89 |
| CFinder | 84 | 7.46 | 80.06 | 4.63 | 6.03 | 4.66 |
Cluster Number: the number of clusters identified by each method; Cluster Size: the average number of proteins in each cluster; Discard (%): the percentage of proteins not assigned to any cluster; GO: the average -log p-values (adjusted) of all detected clusters for Gene Ontology (molecular functions (MF), biological process (BP), and cellular component (CC)).