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. Author manuscript; available in PMC: 2012 Jan 15.
Published in final edited form as: Drug Alcohol Depend. 2010 Sep 15;113(2-3):184–191. doi: 10.1016/j.drugalcdep.2010.07.022

Table 3.

Summary of Selected Treatment Outcome Measures

Disulfiram Dose (mg/day)
Measure 0 62.5 125 250 Test Stat. df p value
N 38 37 38 39
Methadone Maintenance:
Mean methadone dose (mg/day; wks 3–14) 69.2(11.6) 70.0(12.4) 68.4(15.8) 69.5(14.4) F=0.09 3 p=0.96
Mean no. missed doses (wks 3–14) 0.29(0.56) 0.22(0.30) 0.61(1.48) 0.34(0.58) χ2=3.17 3 p=0.36
Opioid Use:
Mean % opioid-positive screens (wk 2) 59.6(41) 68.5(42) 56.1(45) 71.8(40) χ2=3.46 3 p=0.32
Mean % opioid-positive screens (wks 3–14) 49.2(35) 51.7(40) 52.4(39) 58.1(36) χ2=1.10 3 p=0.78
Mean no. bags of heroin used/wk (wk 2) 7.2(14.4) 9.6(24.0) 5.8(9.6) 7.5(13.8) χ2=1.65 3 p=0.65
Mean no. bags of heroin used/wk (wks 3–14) 1.1(3.2) 3.5(5.4) 2.4(2.8) 3.0(4.6) χ2=2.24 3 p=0.53
Mean no. pills opioids used/wk (wk 2) 1.08(3.59) 1.08(3.39) 0.95(3.28) 0.63(3.4) χ2=2.30 3 p=0.51
Mean no. pills opioids used/wk (wks 3–14) 0.90(1.96) 0.26(1.18) 0.27(0.61) 0.20(0.66) χ2=6.11 3 p=0.11
Alcohol Use:
Mean drinks alcohol used/wk (wk 2) 0.02 (0.16) 0.03 (0.17) 0.05 (0.33) 0.84 (3.81) χ2=2.13 3 p=0.54
Mean drinks alcohol used/wk (wks 3–14) 0.24 (0.82) 0.06 (0.13) 0.16 (0.66) 1.01 (3.93) χ2=3.07 3 p=0.38